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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374b228ac5368fc7257268563ba60e8953d6c6a06ea0e41da9986a65dc0b0681' 
  AND token = 'GE5entlqRu9NyTr2ikn9k5NQfhh2RuVmrMSK6TJz43E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}