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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2dbb3becc24d4f26b2c9fc2130d36255e341905e129dac56e3bbdd3886277c0' 
  AND token = 'Y4xS45AiTZCUTvgaxainGrG1Hb7KvFsBy+GwyUjTRcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}