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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a6c8917531f4b858551462fc12b4f224c6dbe1c7afb0fcc744b3f4292158f98' 
  AND token = 'CvTNU1i7RRbU6RJwAhN9vDUvZMXZ3EBZEE4QFR1YU0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}