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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c27b7f6b90e63dcb22fe62d2ce44f5adf388d442540a2fae7da672ca1f09f08' 
  AND token = 'IhEagpOW6qix11lnCi6Ms2Iws0GHCK3mxOEhdjZyWo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}