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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7372f533999f07a1f000eed8df74bd8ef1f796ac4a3124762e2eccfaaa7dbb8c' 
  AND token = 'Ei310OM1Ubj87cadhr6cycGDzQ85qfh+B9dP2rYZfDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}