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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f1a789e3c026f9ccf8cf70b1c971d9144664ee56459860a699a28467fbb7db' 
  AND token = 'jnO/f1dPS1UmqLt/ny30aD7+I0ln0lUk8y0/q6/YfAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}