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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd101be538daf6aad7ae1e1170070dbb9d0143dd3fca22d7a88c736d50e291479' 
  AND token = 'hm0yKgRyr+1Azgzx7dXrqPgkW3ZkkCB6RYeCtca+33Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}