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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a018ae692ca1465d7b6c2a586681b8141e00a1ba7ba377d29e01314261d952' 
  AND token = 'tRZHQ5qVxmg4DYJZ2fz+pfAWIVE4j3Jd2f2h9wHs1F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}