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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '191715f8203e14748908356b8586069ab00cf682f90341e80631b195b4144a36' 
  AND token = 'zDJQ9N3cdR+Sv87TBHn71RKSMRxfVxJkbYyv5w5V2Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}