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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c53a639b65991f33fd07f49dd4a60ec88d1f9de52f9516c9c4087d6523ab59' 
  AND token = 'BbSy8Y2NY+bQcLyO2PHWsVNB0+kB6rC9nLM1u9HspL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}