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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa40341a95f4a1f4b138e6e309c984616ca054272e3da9c0258790c68dedbcd6' 
  AND token = 'MsKNAgjBDGPxcva+x7cPNJS1BB072PM0RzcAWSXQoF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}