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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78f26a42bd06e1805b30ffee2b8283a0f9e626b417b041e889e511b4259667e' 
  AND token = 'a1SuPvK9MsntYD+tjzWQdkduf7NzHQ8OgoN2P+TFDZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}