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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2273e906a9401ee02c52bc1abeb2239a014d83e2b9bae249060b7dd3701228d0' 
  AND token = 'PZnya7F8P1Z/TMcTRl4V3j4kd/YPwaXyKyybVOUZoIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}