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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee335597f57d5797fba9e5ec2f9e87f47e7c706c40731a7907f16f827bd55976' 
  AND token = 'ETna9E9VPqDqgefkswXLgK7wZv9aCzk5jL2TASkLIII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}