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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c82ef7abcd11537e74432e4b6481ddf90031fd8d4a2d4dd289cba992a1c560' 
  AND token = 'zuKE3WMGYoy52e9L7Xec/Uy9oYZ2AbF/93NvMGJIy88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}