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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be1c5cf4d0b8183a52492b3918ccb419a2f6fb80a2c155c6aa29afc046f72655' 
  AND token = 'xgUJuAyvJxuxHAt6lfxP9Xnvvwvlqs2we0Pm0NDHzgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}