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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9749eb828f42d147c2dcffb214d93324d2d345f7e6a456f90b890b5e954db4' 
  AND token = 'DIBHOXto+IfjpVpNCycXXcfEuT1sAA+KNHsG3MUayQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}