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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2466986b5788ebb2a530f256fabe118cb01ce3f76f7042a05a4344bdab4b24f0' 
  AND token = 'oVPl40pq4N0+VTSUDPhPlWoMoHf2445QELpuJKn5zHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}