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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495fc5b04b81b978f3215bee45f016c9a276850808a0a27a1e3855ab502ff5fd' 
  AND token = 'WOb1yG+bCB+zPlc1wIrCgu3eufxEpcx7G+cufZOdB5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}