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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a3d9faa0119c9aa27f17e61b16b95c3599379ec708251bb217b746099f06ec' 
  AND token = 'z37N2ZTBWkL610UQnPjatCKUlW16280rye/U18KqMmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}