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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2660049b3b3bf7d77217b93c0738e850ee9e9f53cda85f3aca6208e0a7aea44c' 
  AND token = 'ZMS2L9PFEJxrG2lxJcFY4waa4fm56/RR0H7+tmKh/zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}