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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2407ac620d40e20b4c77f0149303d78429b02548eca8a35666c62e658b08c53f' 
  AND token = '677KcQbANwJnGI9A8xKUGQfT035cDTU6Y64EGlO+Sog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}