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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e52c22575a9bd5da43899843e5801d78a56dceb573aa1a020d3954b417e901' 
  AND token = 'jYZv7ELMxHAD767VZJLQMVxlFdKEue1l7VqK5orC338=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}