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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf4f5d3fd1ecad367671303acce013ebd29027d8e83c5dac2b6e66f9237a4b8' 
  AND token = 'hpGz5r8jptoLCGI4Vpz9qgTkpTWO1Ppjc6hQnZWTYtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}