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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a589226f62df57b4530dbeb620dfa17f2978ff2679c4c4cdd4fa5dc6f269e9f' 
  AND token = 'wBsSHUEc9IjuhXA8hFWOJ4x4KiO+SpV3EaZgHQkayF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}