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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61a964e29569e8c6733ca2db08279b5f0c2a1814f4f965d8dc0cc0698c016be' 
  AND token = 'rvAw8HJ0Q7HKMreg7SIlMxFdBd5nvVWhDFxCfQe5Br0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}