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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4f23a26b716381aad2234ae46ba61d5ad7dab4656860e0d85e8482cd9c662e' 
  AND token = 'jMeoyKG6VqJa0XMytLGLtSnqGqn5tdSEUoJl1tJxDRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}