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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f247aaded1a0a5d844c84263101250f77d9647f6e5159f15d7f7a9126b01c46' 
  AND token = 'rIH5/JXxI0datSDKQ8Cka4OqvyVpt50hsoGETHY/xL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}