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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efae07993483f743a9302503a1cc9d373f81c0e55c0cb50386e17b669378f887' 
  AND token = 'FAHz5obulSXY73An09SEXpizUWnHgm7b2KCFD9p6khM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}