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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'effb302515a6b060a363e946e7e1c49717a51d7f5c97a7fceeae3d4243574fd1' 
  AND token = 'l0EeCt0+UXKCK4CVbYN5b3QaKhHc10Txi5Euo+UmpeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}