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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2b51750197d247c44f00d674443465a40db99c346b75caa775aff89ca7ea22' 
  AND token = 'lJxOl8wT3V3GZ9+TDT0lhpSyUbR7ieL9M/hCRcQjSAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}