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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1751ba7452d0dafd1ff1fdbba3091cf3f5bc6f323e74efa5845d9c2b532e26bd' 
  AND token = 'r9Wdb6EVI3kX5I8B0FD9r2YMpDaMizqmVPohdz1rzqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}