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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75df7da577e594b252cb1ad33e430c1e8865cd129666297c38316f1cac09a906' 
  AND token = 'm6Rar6Em9JsRv03vfFl8VavMg/uzu5jN7jJ0NXSDpLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}