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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7db4040e6500536aa9eeafe929d1be8e6f20c148cf3f4cda26df07d0a180d3' 
  AND token = 'C/dY8AUFGKVvMbDtuNxLHduup8/X7bZvIWTNrocvbkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}