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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748e53bb6ecda6c11d4aaefd47cea7372c5053205a542a2f46e1d2879912cd74' 
  AND token = 'yqLDUNmPvBn4yrK0qkjx5S6Ubg7wlp2DkbZ9SFb7BOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}