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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b61b62b805dcd14baf6aa1004ef9d2b4e6aab2ade4cefd3f6d2296ad16c6af' 
  AND token = 'RzeN0uAe+1xytApmloB2KEk2Re7DiqJJsotZ9xPwLUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}