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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f43f9887b701c7221e74869058b63b57a6b6f2ef65e03160b70853e62238ef9' 
  AND token = 'eC5t39lDYp2S2JXHnMOrgXiVT8lXOqYsm1zc43hy5wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}