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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17fc5fee01ff1c72f6821ef49f986c4cbfdba60a52d65b20b5293bd5a76069a5' 
  AND token = 'A0AxkZ0K2msPzApjSRV/VuEdOIPhMURdVA+TZ5D1XxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}