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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c479eb4168a060303b4e283df1a4586eed9eb7a86e94d4c4cfe79527ea77d82' 
  AND token = 'V8jabNnysO5+mKakTgyXoYRYEtDnv1LZ9anCojcNV2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}