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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8bdc5730d76cead46d58bd7553ea4bd5d72f966f0f1a22440b83a47b0525693' 
  AND token = 'Buh5C54fRxs45fsFoUiO7vodlv3RsUqlWzHWL2IZtJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}