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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '087516627aadc13fca630698e872233cc57bf961b34ffb61c0f734c386abb9d8' 
  AND token = 'to8P5MWfoM5/HKW+7fA3s/TJbJrK5qiEt98xi+awwZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}