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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ba8e8c0147981df2e02d093b882b20c646ce941f2a790b7b869e27d51092ae9' 
  AND token = 'mi3A4VZyud18eDOH28Y9K22UTohlaz6NmOAm/0Fu41A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}