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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46a103d7472a0a4dcc287dc57e2aac61134f3aae3f763db81117dadc3375634' 
  AND token = 'v+SwiY2zZWRH5Wbg7waMCRcfbC3hd9t0prf+lt7Y8Mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}