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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e40b4d8a2cf4e2dadf1b8be288219663891b7098dfd5811d5b4cd5354c01f05' 
  AND token = 'O2+BcxupKSDTzEQJRilTNEKfz4GjPN3WUj43Qzr/e3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}