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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c322b18c4dbb50d1ad954b80e96a67ddb39c007f3f14ac9dab21a60b473c4d8b' 
  AND token = 'Kj0yiFW35P4jrTz35aAZ/mQV+0kKdVhZn7oOIIKzRA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}