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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d0159c06b4d626a1f8596b5d2bcc90567d160f0d5701ac14affdb8c510d7b8' 
  AND token = '+ebv41NbxzPWZxufoxeQqwbkGoPed81yCp0/6002L54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}