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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf72f3ac96c361ee4a303c02c6775b99f781a7a703b6c6844d4aafe8e185fd0' 
  AND token = 'Vb9DGqXW1VAiQf032fBLh1wOJgvlxOJaQVr1P7+RneA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}