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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8fc763413d4ed538aee382236e185e6abecc9dadbc01e3b57bf55a3a8e4dfff' 
  AND token = 'Kkg6qjZMbeNcD5ig3TrAzMSJrH8xhos+4o5Cy5lRua0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}