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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e7c59dcd69c8219c5f8081ccf05c91389e072755025904943c741d34a81d6a' 
  AND token = 'a18OOsGmXkehehWPe5qT8/qLj0VtISgQkf2uLbu+U0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}