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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a56d7543f7d11b0098cd2eca64c46181f274e7c3623db4a6885b91f3359e0bf1' 
  AND token = 'gEUY3qKB3MhRRgQBN42caf/B1SIt/IlmhUm5le5kiDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}